PRECISE-TBI | Preclinical TBI bibliography

Bibliography

The PRECISE-TBI bibliography of preclinical papers is a curated list of papers that will be included in the PRECISE-TBI preclinical model catalog. Papers will be added to the model catalog in smaller batches to ensure proper curation of all metadata. Please select a model below for the current list of papers to be included in the catalog.

> Controlled Cortical Impact Model (2,079 references)

Showing the first 102 of 2,079 references. Additional references will be added in future batches.

Liu MC, Akle V, Zheng W, Dave JR, Tortella FC, Hayes RL, Wang KK. Comparing calpain- and caspase-3-mediated degradation patterns in traumatic brain injury by differential proteome analysis. Biochem J. 2006 Mar 15;394(Pt 3):715-25. doi: 10.1042/BJ20050905. PMID:16351572; PMC1383722
Hainsworth AH, Bermpohl D, Webb TE, Darwish R, Fiskum G, Qiu J, McCarthy D, Moskowitz MA, Whalen MJ. Expression of cellular FLICE inhibitory proteins (cFLIP) in normal and traumatic murine and human cerebral cortex. J Cereb Blood Flow Metab. 2005 Aug;25(8):1030-40. doi: 10.1038/sj.jcbfm.9600104. PMID:15815586; PMC1266275
Mahmood A, Lu D, Qu C, Goussev A, Chopp M. Human marrow stromal cell treatment provides long-lasting benefit after traumatic brain injury in rats. Neurosurgery. 2005 Nov;57(5):1026-31; discussion 1026-31. doi: 10.1227/01.neu.0000181369.76323.50. PMID:16284572; PMC1570382
Scherbel U, Raghupathi R, Nakamura M, Saatman KE, Trojanowski JQ, Neugebauer E, Marino MW, McIntosh TK. Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury. Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8721-6. doi: 10.1073/pnas.96.15.8721. PMID:10411942; PMC17583
Redell JB, Dash PK. Traumatic brain injury stimulates hippocampal catechol-O-methyl transferase expression in microglia. Neurosci Lett. 2007 Feb 8;413(1):36-41. doi: 10.1016/j.neulet.2006.11.060. Epub 2006 Dec 15. PMID:17240060; PMC1857315
Brody DL, Holtzman DM. Morris water maze search strategy analysis in PDAPP mice before and after experimental traumatic brain injury. Exp Neurol. 2006 Feb;197(2):330-40. doi: 10.1016/j.expneurol.2005.10.020. Epub 2005 Nov 23. PMID:16309676; PMC1913184
Onyszchuk G, Al-Hafez B, He YY, Bilgen M, Berman NE, Brooks WM. A mouse model of sensorimotor controlled cortical impact: characterization using longitudinal magnetic resonance imaging, behavioral assessments and histology. J Neurosci Methods. 2007 Mar 15;160(2):187-96. doi: 10.1016/j.jneumeth.2006.09.007. Epub 2006 Oct 16. PMID:17049995; PMC1941707 **In Model Catalog**
Yakovlev AG, Di X, Movsesyan V, Mullins PG, Wang G, Boulares H, Zhang J, Xu M, Faden AI. Presence of DNA fragmentation and lack of neuroprotective effect in DFF45 knockout mice subjected to traumatic brain injury. Mol Med. 2001 Mar;7(3):205-16. PMID:11471558; PMC1950023
Deng Y, Thompson BM, Gao X, Hall ED. Temporal relationship of peroxynitrite-induced oxidative damage, calpain-mediated cytoskeletal degradation and neurodegeneration after traumatic brain injury. Exp Neurol. 2007 May;205(1):154-65. doi: 10.1016/j.expneurol.2007.01.023. Epub 2007 Feb 3. PMID:17349624; PMC1950332
Lu D, Qu C, Goussev A, Jiang H, Lu C, Schallert T, Mahmood A, Chen J, Li Y, Chopp M. Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury. J Neurotrauma. 2007 Jul;24(7):1132-46. doi: 10.1089/neu.2007.0288. PMID:17610353; PMC1971229
Wagner AK, Kline AE, Ren D, Willard LA, Wenger MK, Zafonte RD, Dixon CE. Gender associations with chronic methylphenidate treatment and behavioral performance following experimental traumatic brain injury. Behav Brain Res. 2007 Aug 6;181(2):200-9. doi: 10.1016/j.bbr.2007.04.006. Epub 2007 Apr 20. PMID:17517440; PMC1974874
Venneti S, Wagner AK, Wang G, Slagel SL, Chen X, Lopresti BJ, Mathis CA, Wiley CA. The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds specifically to microglia in a rat model of traumatic brain injury: implications for PET imaging. Exp Neurol. 2007 Sep;207(1):118-27. doi: 10.1016/j.expneurol.2007.06.003. Epub 2007 Jun 19. PMID:17658516; PMC2042945
Yoshimura S, Teramoto T, Whalen MJ, Irizarry MC, Takagi Y, Qiu J, Harada J, Waeber C, Breakefield XO, Moskowitz MA. FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice. J Clin Invest. 2003 Oct;112(8):1202-10. doi: 10.1172/JCI16618. PMID:14561705; PMC213483
Brody DL, Mac Donald C, Kessens CC, Yuede C, Parsadanian M, Spinner M, Kim E, Schwetye KE, Holtzman DM, Bayly PV. Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injury. J Neurotrauma. 2007 Apr;24(4):657-73. doi: 10.1089/neu.2006.0011. PMID:17439349; PMC2435168 **In Model Catalog**
Griesbach GS, Hovda DA, Gomez-Pinilla F, Sutton RL. Voluntary exercise or amphetamine treatment, but not the combination, increases hippocampal brain-derived neurotrophic factor and synapsin I following cortical contusion injury in rats. Neuroscience. 2008 Jun 23;154(2):530-40. doi: 10.1016/j.neuroscience.2008.04.003. Epub 2008 Apr 9. PMID:18479829; PMC2441485 **In Model Catalog**
Hoane MR, Pierce JL, Holland MA, Anderson GD. Nicotinamide treatment induces behavioral recovery when administered up to 4 hours following cortical contusion injury in the rat. Neuroscience. 2008 Jun 26;154(3):861-8. doi: 10.1016/j.neuroscience.2008.04.044. Epub 2008 May 2. PMID:18514428; PMC2495083
Statler KD, Swank S, Abildskov T, Bigler ED, White HS. Traumatic brain injury during development reduces minimal clonic seizure thresholds at maturity. Epilepsy Res. 2008 Aug;80(2-3):163-70. doi: 10.1016/j.eplepsyres.2008.04.001. Epub 2008 May 19. PMID:18490145; PMC2542942
Cheng JP, Hoffman AN, Zafonte RD, Kline AE. A delayed and chronic treatment regimen with the 5-HT1A receptor agonist 8-OH-DPAT after cortical impact injury facilitates motor recovery and acquisition of spatial learning. Behav Brain Res. 2008 Dec 1;194(1):79-85. doi: 10.1016/j.bbr.2008.06.025. Epub 2008 Jul 1. PMID:18638506; PMC2568997
Conte V, Raghupathi R, Watson DJ, Fujimoto S, Royo NC, Marklund N, Stocchetti N, McIntosh TK. TrkB gene transfer does not alter hippocampal neuronal loss and cognitive deficits following traumatic brain injury in mice. Restor Neurol Neurosci. 2008;26(1):45-56. PMID:18431005; PMC2580053
Neumann M, Wang Y, Kim S, Hong SM, Jeng L, Bilgen M, Liu J. Assessing gait impairment following experimental traumatic brain injury in mice. J Neurosci Methods. 2009 Jan 15;176(1):34-44. doi: 10.1016/j.jneumeth.2008.08.026. Epub 2008 Sep 3. PMID:18805438; PMC2588469
Strauss KI, Narayan RK, Raghupathi R. Common patterns of bcl-2 family gene expression in two traumatic brain injury models. Neurotox Res. 2004;6(4):333-42. doi: 10.1007/BF03033444. PMID:15545017; PMC2590760
Xiong Y, Mahmood A, Lu D, Qu C, Kazmi H, Goussev A, Zhang ZG, Noguchi CT, Schallert T, Chopp M. Histological and functional outcomes after traumatic brain injury in mice null for the erythropoietin receptor in the central nervous system. Brain Res. 2008 Sep 16;1230:247-57. doi: 10.1016/j.brainres.2008.06.127. Epub 2008 Jul 15. PMID:18657521; PMC2593645
Yi JH, Park SW, Brooks N, Lang BT, Vemuganti R. PPARgamma agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms. Brain Res. 2008 Dec 9;1244:164-72. doi: 10.1016/j.brainres.2008.09.074. Epub 2008 Oct 9. PMID:18948087; PMC2603294
Yu TS, Zhang G, Liebl DJ, Kernie SG. Traumatic brain injury-induced hippocampal neurogenesis requires activation of early nestin-expressing progenitors. J Neurosci. 2008 Nov 26;28(48):12901-12. doi: 10.1523/JNEUROSCI.4629-08.2008. PMID:19036984; PMC2605967
Chen SF, Hsu CW, Huang WH, Wang JY. Post-injury baicalein improves histological and functional outcomes and reduces inflammatory cytokines after experimental traumatic brain injury. Br J Pharmacol. 2008 Dec;155(8):1279-96. doi: 10.1038/bjp.2008.345. Epub 2008 Sep 8. PMID:18776918; PMC2607198
Sandhir R, Onyszchuk G, Berman NE. Exacerbated glial response in the aged mouse hippocampus following controlled cortical impact injury. Exp Neurol. 2008 Oct;213(2):372-80. doi: 10.1016/j.expneurol.2008.06.013. Epub 2008 Jul 2. PMID:18692046; PMC2662478
Scafidi S, O'Brien J, Hopkins I, Robertson C, Fiskum G, McKenna M. Delayed cerebral oxidative glucose metabolism after traumatic brain injury in young rats. J Neurochem. 2009 May;109 Suppl 1(Suppl 1):189-97. doi: 10.1111/j.1471-4159.2009.05896.x. PMID:19393027; PMC2692097
Wagner AK, Drewencki LL, Chen X, Santos FR, Khan AS, Harun R, Torres GE, Michael AC, Dixon CE. Chronic methylphenidate treatment enhances striatal dopamine neurotransmission after experimental traumatic brain injury. J Neurochem. 2009 Feb;108(4):986-97. doi: 10.1111/j.1471-4159.2008.05840.x. Epub 2008 Dec 10. PMID:19077052; PMC2692956
Dennis AM, Haselkorn ML, Vagni VA, Garman RH, Janesko-Feldman K, Bayir H, Clark RS, Jenkins LW, Dixon CE, Kochanek PM. Hemorrhagic shock after experimental traumatic brain injury in mice: effect on neuronal death. J Neurotrauma. 2009 Jun;26(6):889-99. doi: 10.1089/neu.2008.0512. PMID:18781889; PMC2694227 **In Model Catalog**
Statler KD, Scheerlinck P, Pouliot W, Hamilton M, White HS, Dudek FE. A potential model of pediatric posttraumatic epilepsy. Epilepsy Res. 2009 Oct;86(2-3):221-3. doi: 10.1016/j.eplepsyres.2009.05.006. Epub 2009 Jun 10. PMID:19520549; PMC2702176
Shelton SB, Pettigrew DB, Hermann AD, Zhou W, Sullivan PM, Crutcher KA, Strauss KI. A simple, efficient tool for assessment of mice after unilateral cortex injury. J Neurosci Methods. 2008 Mar 15;168(2):431-42. doi: 10.1016/j.jneumeth.2007.11.003. Epub 2007 Nov 19. PMID:18164073; PMC2702871
Whalen MJ, Dalkara T, You Z, Qiu J, Bermpohl D, Mehta N, Suter B, Bhide PG, Lo EH, Ericsson M, Moskowitz MA. Acute plasmalemma permeability and protracted clearance of injured cells after controlled cortical impact in mice. J Cereb Blood Flow Metab. 2008 Mar;28(3):490-505. doi: 10.1038/sj.jcbfm.9600544. Epub 2007 Aug 22. PMID:17713463; PMC2711980
Tehranian R, Rose ME, Vagni V, Pickrell AM, Griffith RP, Liu H, Clark RS, Dixon CE, Kochanek PM, Graham SH. Disruption of Bax protein prevents neuronal cell death but produces cognitive impairment in mice following traumatic brain injury. J Neurotrauma. 2008 Jul;25(7):755-67. doi: 10.1089/neu.2007.0441. PMID:18627254; PMC2717742
Mahmood A, Goussev A, Lu D, Qu C, Xiong Y, Kazmi H, Chopp M. Long-lasting benefits after treatment of traumatic brain injury (TBI) in rats with combination therapy of marrow stromal cells (MSCs) and simvastatin. J Neurotrauma. 2008 Dec;25(12):1441-7. doi: 10.1089/neu.2007.0495. PMID:19072586; PMC2719878
Kochanek AR, Kline AE, Gao WM, Chadha M, Lai Y, Clark RS, Dixon CE, Jenkins LW. Gel-based hippocampal proteomic analysis 2 weeks following traumatic brain injury to immature rats using controlled cortical impact. Dev Neurosci. 2006;28(4-5):410-9. doi: 10.1159/000094167. PMID:16943664; PMC2721469
Szmydynger-Chodobska J, Strazielle N, Zink BJ, Ghersi-Egea JF, Chodobski A. The role of the choroid plexus in neutrophil invasion after traumatic brain injury. J Cereb Blood Flow Metab. 2009 Sep;29(9):1503-16. doi: 10.1038/jcbfm.2009.71. Epub 2009 May 27. PMID:19471279; PMC2736364
Ahmad M, Rose ME, Vagni V, Griffith RP, Dixon CE, Kochanek PM, Hickey RW, Graham SH. Genetic disruption of cyclooxygenase-2 does not improve histological or behavioral outcome after traumatic brain injury in mice. J Neurosci Res. 2008 Dec;86(16):3605-12. doi: 10.1002/jnr.21809. PMID:18711748; PMC2737709
Mahmood A, Goussev A, Kazmi H, Qu C, Lu D, Chopp M. Long-term benefits after treatment of traumatic brain injury with simvastatin in rats. Neurosurgery. 2009 Jul;65(1):187-91; discussion 191-2. doi: 10.1227/01.NEU.0000343540.24780.D6. PMID:19574841; PMC2741617
Zhang Y, Xiong Y, Mahmood A, Meng Y, Qu C, Schallert T, Chopp M. Therapeutic effects of erythropoietin on histological and functional outcomes following traumatic brain injury in rats are independent of hematocrit. Brain Res. 2009 Oct 19;1294:153-64. doi: 10.1016/j.brainres.2009.07.077. Epub 2009 Jul 30. PMID:19646970; PMC2746872
Griesbach GS, Sutton RL, Hovda DA, Ying Z, Gomez-Pinilla F. Controlled contusion injury alters molecular systems associated with cognitive performance. J Neurosci Res. 2009 Feb 15;87(3):795-805. doi: 10.1002/jnr.21893. PMID:18831070; PMC2747484
Li B, Mahmood A, Lu D, Wu H, Xiong Y, Qu C, Chopp M. Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury. Neurosurgery. 2009 Jul;65(1):179-85; discussion 185-6. doi: 10.1227/01.NEU.0000346272.76537.DC. PMID:19574840; PMC2749520
Kelso ML, Scheff SW, Pauly JR, Loftin CD. Effects of genetic deficiency of cyclooxygenase-1 or cyclooxygenase-2 on functional and histological outcomes following traumatic brain injury in mice. BMC Neurosci. 2009 Aug 31;10:108. doi: 10.1186/1471-2202-10-108. PMID:19719848; PMC2751761
Mbye LH, Singh IN, Carrico KM, Saatman KE, Hall ED. Comparative neuroprotective effects of cyclosporin A and NIM811, a nonimmunosuppressive cyclosporin A analog, following traumatic brain injury. J Cereb Blood Flow Metab. 2009 Jan;29(1):87-97. doi: 10.1038/jcbfm.2008.93. Epub 2008 Aug 20. PMID:18714331; PMC2755489
Qu C, Xiong Y, Mahmood A, Kaplan DL, Goussev A, Ning R, Chopp M. Treatment of traumatic brain injury in mice with bone marrow stromal cell-impregnated collagen scaffolds. J Neurosurg. 2009 Oct;111(4):658-65. doi: 10.3171/2009.4.JNS081681. PMID:19425888; PMC2756329
Marklund N, Morales D, Clausen F, Hanell A, Kiwanuka O, Pitkanen A, Gimbel DA, Philipson O, Lannfelt L, Hillered L, Strittmatter SM, McIntosh TK. Functional outcome is impaired following traumatic brain injury in aging Nogo-A/B-deficient mice. Neuroscience. 2009 Oct 6;163(2):540-51. doi: 10.1016/j.neuroscience.2009.06.042. Epub 2009 Jun 23. PMID:19555742; PMC2756649
Wagner AK, Sokoloski JE, Chen X, Harun R, Clossin DP, Khan AS, Andes-Koback M, Michael AC, Dixon CE. Controlled cortical impact injury influences methylphenidate-induced changes in striatal dopamine neurotransmission. J Neurochem. 2009 Aug;110(3):801-10. doi: 10.1111/j.1471-4159.2009.06155.x. Epub 2009 May 8. PMID:19457094; PMC2757306
Khan M, Im YB, Shunmugavel A, Gilg AG, Dhindsa RK, Singh AK, Singh I. Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact. J Neuroinflammation. 2009 Nov 4;6:32. doi: 10.1186/1742-2094-6-32. PMID:19889224; PMC2777134
Quigley A, Tan AA, Hoane MR. The effects of hypertonic saline and nicotinamide on sensorimotor and cognitive function following cortical contusion injury in the rat. Brain Res. 2009 Dec 22;1304:138-48. doi: 10.1016/j.brainres.2009.09.062. Epub 2009 Sep 23. PMID:19781534; PMC2784246
Petraglia AL, Marky AH, Walker C, Thiyagarajan M, Zlokovic BV. Activated protein C is neuroprotective and mediates new blood vessel formation and neurogenesis after controlled cortical impact. Neurosurgery. 2010 Jan;66(1):165-71; discussion 171-2. doi: 10.1227/01.NEU.0000363148.49779.68. PMID:20023547; PMC2800370
Ji YC, Kim YB, Park SW, Hwang SN, Min BK, Hong HJ, Kwon JT, Suk JS. Neuroprotective effect of ginseng total saponins in experimental traumatic brain injury. J Korean Med Sci. 2005 Apr;20(2):291-6. doi: 10.3346/jkms.2005.20.2.291. PMID:15832003; PMC2808608
Bales JW, Ma X, Yan HQ, Jenkins LW, Dixon CE. Expression of protein phosphatase 2B (calcineurin) subunit A isoforms in rat hippocampus after traumatic brain injury. J Neurotrauma. 2010 Jan;27(1):109-20. doi: 10.1089/neu.2009.1072. PMID:19751097; PMC2812667
Sandhir R, Berman NE. Age-dependent response of CCAAT/enhancer binding proteins following traumatic brain injury in mice. Neurochem Int. 2010 Jan;56(1):188-93. doi: 10.1016/j.neuint.2009.10.002. Epub 2009 Oct 13. PMID:19833158; PMC2815015 **In Model Catalog**
Anderson KJ, Scheff SW, Miller KM, Roberts KN, Gilmer LK, Yang C, Shaw G. The phosphorylated axonal form of the neurofilament subunit NF-H (pNF-H) as a blood biomarker of traumatic brain injury. J Neurotrauma. 2008 Sep;25(9):1079-85. doi: 10.1089/neu.2007.0488. PMID:18729720; PMC2820728
Harris NG, Carmichael ST, Hovda DA, Sutton RL. Traumatic brain injury results in disparate regions of chondroitin sulfate proteoglycan expression that are temporally limited. J Neurosci Res. 2009 Oct;87(13):2937-50. doi: 10.1002/jnr.22115. PMID:19437549; PMC2821049
Harris NG, Mironova YA, Hovda DA, Sutton RL. Pericontusion axon sprouting is spatially and temporally consistent with a growth-permissive environment after traumatic brain injury. J Neuropathol Exp Neurol. 2010 Feb;69(2):139-54. doi: 10.1097/NEN.0b013e3181cb5bee. PMID:20084019; PMC2821052
Tejima E, Guo S, Murata Y, Arai K, Lok J, van Leyen K, Rosell A, Wang X, Lo EH. Neuroprotective effects of overexpressing tissue inhibitor of metalloproteinase TIMP-1. J Neurotrauma. 2009 Nov;26(11):1935-41. doi: 10.1089/neu.2009.0959. PMID:19469687; PMC2822804
Anderson J, Sandhir R, Hamilton ES, Berman NE. Impaired expression of neuroprotective molecules in the HIF-1alpha pathway following traumatic brain injury in aged mice. J Neurotrauma. 2009 Sep;26(9):1557-66. doi: 10.1089/neu.2008.0765. PMID:19203226; PMC2822808
Foley LM, Hitchens TK, Ho C, Janesko-Feldman KL, Melick JA, Bayir H, Kochanek PM. Magnetic resonance imaging assessment of macrophage accumulation in mouse brain after experimental traumatic brain injury. J Neurotrauma. 2009 Sep;26(9):1509-19. doi: 10.1089/neu.2008.0747. PMID:19663686; PMC2822809
Arun P, Ariyannur PS, Moffett JR, Xing G, Hamilton K, Grunberg NE, Ives JA, Namboodiri AM. Metabolic acetate therapy for the treatment of traumatic brain injury. J Neurotrauma. 2010 Jan;27(1):293-8. doi: 10.1089/neu.2009.0994. PMID:19803785; PMC2824219
Xiong Y, Mahmood A, Qu C, Kazmi H, Zhang ZG, Noguchi CT, Schallert T, Chopp M. Erythropoietin improves histological and functional outcomes after traumatic brain injury in mice in the absence of the neural erythropoietin receptor. J Neurotrauma. 2010 Jan;27(1):205-15. doi: 10.1089/neu.2009.1001. PMID:19715391; PMC2824224
Madathil SK, Evans HN, Saatman KE. Temporal and regional changes in IGF-1/IGF-1R signaling in the mouse brain after traumatic brain injury. J Neurotrauma. 2010 Jan;27(1):95-107. doi: 10.1089/neu.2009.1002. PMID:19751099; PMC2824225
Onyszchuk G, LeVine SM, Brooks WM, Berman NE. Post-acute pathological changes in the thalamus and internal capsule in aged mice following controlled cortical impact injury: a magnetic resonance imaging, iron histochemical, and glial immunohistochemical study. Neurosci Lett. 2009 Mar 13;452(2):204-8. doi: 10.1016/j.neulet.2009.01.049. Epub 2009 Jan 23. PMID:19383440; PMC2829973
You Z, Savitz SI, Yang J, Degterev A, Yuan J, Cuny GD, Moskowitz MA, Whalen MJ. Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice. J Cereb Blood Flow Metab. 2008 Sep;28(9):1564-73. doi: 10.1038/jcbfm.2008.44. Epub 2008 May 21. PMID:18493258; PMC2831087
Prins ML, Hovda DA. The effects of age and ketogenic diet on local cerebral metabolic rates of glucose after controlled cortical impact injury in rats. J Neurotrauma. 2009 Jul;26(7):1083-93. doi: 10.1089/neu.2008.0769. PMID:19226210; PMC2843133
Appelberg KS, Hovda DA, Prins ML. The effects of a ketogenic diet on behavioral outcome after controlled cortical impact injury in the juvenile and adult rat. J Neurotrauma. 2009 Apr;26(4):497-506. doi: 10.1089/neu.2008.0664. PMID:19231995; PMC2843134
Liu MC, Akinyi L, Scharf D, Mo J, Larner SF, Muller U, Oli MW, Zheng W, Kobeissy F, Papa L, Lu XC, Dave JR, Tortella FC, Hayes RL, Wang KK. Ubiquitin C-terminal hydrolase-L1 as a biomarker for ischemic and traumatic brain injury in rats. Eur J Neurosci. 2010 Feb;31(4):722-32. doi: 10.1111/j.1460-9568.2010.07097.x. PMID:20384815; PMC2855688
Exo JL, Shellington DK, Bayir H, Vagni VA, Janesco-Feldman K, Ma L, Hsia CJ, Clark RS, Jenkins LW, Dixon CE, Kochanek PM. Resuscitation of traumatic brain injury and hemorrhagic shock with polynitroxylated albumin, hextend, hypertonic saline, and lactated Ringer's: Effects on acute hemodynamics, survival, and neuronal death in mice. J Neurotrauma. 2009 Dec;26(12):2403-8. doi: 10.1089/neu.2009.0980. PMID:19691424; PMC2864460
Zahedi K, Huttinger F, Morrison R, Murray-Stewart T, Casero RA, Strauss KI. Polyamine catabolism is enhanced after traumatic brain injury. J Neurotrauma. 2010 Mar;27(3):515-25. doi: 10.1089/neu.2009.1097. PMID:19968558; PMC2867553
Harting MT, Sloan LE, Jimenez F, Baumgartner J, Cox CS Jr. Subacute neural stem cell therapy for traumatic brain injury. J Surg Res. 2009 May 15;153(2):188-94. doi: 10.1016/j.jss.2008.03.037. Epub 2008 Apr 23. PMID:18694578; PMC2874889
Harting MT, Jimenez F, Xue H, Fischer UM, Baumgartner J, Dash PK, Cox CS. Intravenous mesenchymal stem cell therapy for traumatic brain injury. J Neurosurg. 2009 Jun;110(6):1189-97. doi: 10.3171/2008.9.JNS08158. PMID:19301973; PMC2889620
Walker PA, Harting MT, Jimenez F, Shah SK, Pati S, Dash PK, Cox CS Jr. Direct intrathecal implantation of mesenchymal stromal cells leads to enhanced neuroprotection via an NFkappaB-mediated increase in interleukin-6 production. Stem Cells Dev. 2010 Jun;19(6):867-76. doi: 10.1089/scd.2009.0188. PMID:19775197; PMC2891441
Wang WX, Wilfred BR, Madathil SK, Tang G, Hu Y, Dimayuga J, Stromberg AJ, Huang Q, Saatman KE, Nelson PT. miR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative disease. Am J Pathol. 2010 Jul;177(1):334-45. doi: 10.2353/ajpath.2010.091202. Epub 2010 May 20. PMID:20489155; PMC2893676
Xiong Y, Mahmood A, Meng Y, Zhang Y, Qu C, Schallert T, Chopp M. Delayed administration of erythropoietin reducing hippocampal cell loss, enhancing angiogenesis and neurogenesis, and improving functional outcome following traumatic brain injury in rats: comparison of treatment with single and triple dose. J Neurosurg. 2010 Sep;113(3):598-608. doi: 10.3171/2009.9.JNS09844. PMID:19817538; PMC2898921
Laird MD, Sukumari-Ramesh S, Swift AE, Meiler SE, Vender JR, Dhandapani KM. Curcumin attenuates cerebral edema following traumatic brain injury in mice: a possible role for aquaporin-4?. J Neurochem. 2010 May;113(3):637-48. doi: 10.1111/j.1471-4159.2010.06630.x. Epub 2010 Jan 20. PMID:20132469; PMC2911034
Dohi K, Ohtaki H, Nakamachi T, Yofu S, Satoh K, Miyamoto K, Song D, Tsunawaki S, Shioda S, Aruga T. Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury. J Neuroinflammation. 2010 Jul 26;7:41. doi: 10.1186/1742-2094-7-41. PMID:20659322; PMC2917406
Abdel Baki SG, Schwab B, Haber M, Fenton AA, Bergold PJ. Minocycline synergizes with N-acetylcysteine and improves cognition and memory following traumatic brain injury in rats. PLoS One. 2010 Aug 31;5(8):e12490. doi: 10.1371/journal.pone.0012490. PMID:20824218; PMC2930858
Zhang Y, Xiong Y, Mahmood A, Meng Y, Liu Z, Qu C, Chopp M. Sprouting of corticospinal tract axons from the contralateral hemisphere into the denervated side of the spinal cord is associated with functional recovery in adult rat after traumatic brain injury and erythropoietin treatment. Brain Res. 2010 Sep 24;1353:249-57. doi: 10.1016/j.brainres.2010.07.046. Epub 2010 Jul 21. PMID:20654589; PMC2933297
Hanell A, Clausen F, Bjork M, Jansson K, Philipson O, Nilsson LN, Hillered L, Weinreb PH, Lee D, McIntosh TK, Gimbel DA, Strittmatter SM, Marklund N. Genetic deletion and pharmacological inhibition of Nogo-66 receptor impairs cognitive outcome after traumatic brain injury in mice. J Neurotrauma. 2010 Jul;27(7):1297-309. doi: 10.1089/neu.2009.1255. PMID:20486800; PMC2942864
Kuypers NJ, Hoane MR. Pyridoxine administration improves behavioral and anatomical outcome after unilateral contusion injury in the rat. J Neurotrauma. 2010 Jul;27(7):1275-82. doi: 10.1089/neu.2010.1327. PMID:20486803; PMC2942865
Bonneh-Barkay D, Zagadailov P, Zou H, Niyonkuru C, Figley M, Starkey A, Wang G, Bissel SJ, Wiley CA, Wagner AK. YKL-40 expression in traumatic brain injury: an initial analysis. J Neurotrauma. 2010 Jul;27(7):1215-23. doi: 10.1089/neu.2010.1310. PMID:20486806; PMC2942903
Yang J, You Z, Kim HH, Hwang SK, Khuman J, Guo S, Lo EH, Whalen MJ. Genetic analysis of the role of tumor necrosis factor receptors in functional outcome after traumatic brain injury in mice. J Neurotrauma. 2010 Jun;27(6):1037-46. doi: 10.1089/neu.2009.1229. PMID:20205514; PMC2943499
Singleton RH, Yan HQ, Fellows-Mayle W, Dixon CE. Resveratrol attenuates behavioral impairments and reduces cortical and hippocampal loss in a rat controlled cortical impact model of traumatic brain injury. J Neurotrauma. 2010 Jun;27(6):1091-9. doi: 10.1089/neu.2010.1291. PMID:20560755; PMC2943501
Sozda CN, Hoffman AN, Olsen AS, Cheng JP, Zafonte RD, Kline AE. Empirical comparison of typical and atypical environmental enrichment paradigms on functional and histological outcome after experimental traumatic brain injury. J Neurotrauma. 2010 Jun;27(6):1047-57. doi: 10.1089/neu.2010.1313. PMID:20334496; PMC2943502
Mao H, Jin X, Zhang L, Yang KH, Igarashi T, Noble-Haeusslein LJ, King AI. Finite element analysis of controlled cortical impact-induced cell loss. J Neurotrauma. 2010 May;27(5):877-88. doi: 10.1089/neu.2008.0616. PMID:20199194; PMC2943943
Haselkorn ML, Shellington DK, Jackson EK, Vagni VA, Janesko-Feldman K, Dubey RK, Gillespie DG, Cheng D, Bell MJ, Jenkins LW, Homanics GE, Schnermann J, Kochanek PM. Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice. J Neurotrauma. 2010 May;27(5):901-10. doi: 10.1089/neu.2009.1075. PMID:20121416; PMC2943944
Trabold R, Eros C, Zweckberger K, Relton J, Beck H, Nussberger J, Muller-Esterl W, Bader M, Whalley E, Plesnila N. The role of bradykinin B(1) and B(2) receptors for secondary brain damage after traumatic brain injury in mice. J Cereb Blood Flow Metab. 2010 Jan;30(1):130-9. doi: 10.1038/jcbfm.2009.196. Epub 2009 Sep 23. PMID:19773800; PMC2949094
Immonen R, Heikkinen T, Tahtivaara L, Nurmi A, Stenius TK, Puolivali J, Tuinstra T, Phinney AL, Van Vliet B, Yrjanheikki J, Grohn O. Cerebral blood volume alterations in the perilesional areas in the rat brain after traumatic brain injury--comparison with behavioral outcome. J Cereb Blood Flow Metab. 2010 Jul;30(7):1318-28. doi: 10.1038/jcbfm.2010.15. Epub 2010 Feb 10. PMID:20145657; PMC2949222
Bales JW, Ma X, Yan HQ, Jenkins LW, Dixon CE. Regional calcineurin subunit B isoform expression in rat hippocampus following a traumatic brain injury. Brain Res. 2010 Oct 28;1358:211-20. doi: 10.1016/j.brainres.2010.08.029. Epub 2010 Aug 13. PMID:20713027; PMC2949526
Goffus AM, Anderson GD, Hoane M. Sustained delivery of nicotinamide limits cortical injury and improves functional recovery following traumatic brain injury. Oxid Med Cell Longev. 2010 Mar-Apr;3(2):145-52. doi: 10.4161/oxim.3.2.11315. PMID:20716938; PMC2952098
Schwetye KE, Cirrito JR, Esparza TJ, Mac Donald CL, Holtzman DM, Brody DL. Traumatic brain injury reduces soluble extracellular amyloid-beta in mice: a methodologically novel combined microdialysis-controlled cortical impact study. Neurobiol Dis. 2010 Dec;40(3):555-64. doi: 10.1016/j.nbd.2010.06.018. Epub 2010 Aug 1. PMID:20682338; PMC2955836
Xiong Y, Mahmood A, Meng Y, Zhang Y, Zhang ZG, Morris DC, Chopp M. Treatment of traumatic brain injury with thymosin beta? in rats. J Neurosurg. 2011 Jan;114(1):102-15. doi: 10.3171/2010.4.JNS10118. Epub 2010 May 21. PMID:20486893; PMC2962722
Szmydynger-Chodobska J, Fox LM, Lynch KM, Zink BJ, Chodobski A. Vasopressin amplifies the production of proinflammatory mediators in traumatic brain injury. J Neurotrauma. 2010 Aug;27(8):1449-61. doi: 10.1089/neu.2010.1331. PMID:20504162; PMC2967824
Harris NG, Mironova YA, Hovda DA, Sutton RL. Chondroitinase ABC enhances pericontusion axonal sprouting but does not confer robust improvements in behavioral recovery. J Neurotrauma. 2010 Nov;27(11):1971-82. doi: 10.1089/neu.2010.1470. Epub 2010 Oct 20. PMID:20809786; PMC2978059
Nishibe M, Barbay S, Guggenmos D, Nudo RJ. Reorganization of motor cortex after controlled cortical impact in rats and implications for functional recovery. J Neurotrauma. 2010 Dec;27(12):2221-32. doi: 10.1089/neu.2010.1456. Epub 2010 Nov 22. PMID:20873958; PMC2996815
Thompson SN, Carrico KM, Mustafa AG, Bains M, Hall ED. A pharmacological analysis of the neuroprotective efficacy of the brain- and cell-permeable calpain inhibitor MDL-28170 in the mouse controlled cortical impact traumatic brain injury model. J Neurotrauma. 2010 Dec;27(12):2233-43. doi: 10.1089/neu.2010.1474. PMID:20874056; PMC2996835
Kelso ML, Scheff NN, Scheff SW, Pauly JR. Melatonin and minocycline for combinatorial therapy to improve functional and histopathological deficits following traumatic brain injury. Neurosci Lett. 2011 Jan 13;488(1):60-4. doi: 10.1016/j.neulet.2010.11.003. Epub 2010 Nov 5. PMID:21056621; PMC3010453
Shin SS, Bray ER, Zhang CQ, Dixon CE. Traumatic brain injury reduces striatal tyrosine hydroxylase activity and potassium-evoked dopamine release in rats. Brain Res. 2011 Jan 19;1369:208-15. doi: 10.1016/j.brainres.2010.10.096. Epub 2010 Nov 1. PMID:21047500; PMC3014391
Krajewska M, Xu L, Xu W, Krajewski S, Kress CL, Cui J, Yang L, Irie F, Yamaguchi Y, Lipton SA, Reed JC. Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury. Brain Res. 2011 Jan 25;1370:227-37. doi: 10.1016/j.brainres.2010.11.015. Epub 2010 Nov 12. PMID:21075086; PMC3019258
Sauerbeck A, Gao J, Readnower R, Liu M, Pauly JR, Bing G, Sullivan PG. Pioglitazone attenuates mitochondrial dysfunction, cognitive impairment, cortical tissue loss, and inflammation following traumatic brain injury. Exp Neurol. 2011 Jan;227(1):128-35. doi: 10.1016/j.expneurol.2010.10.003. Epub 2010 Oct 20. PMID:20965168; PMC3019268
Qu C, Mahmood A, Liu XS, Xiong Y, Wang L, Wu H, Li B, Zhang ZG, Kaplan DL, Chopp M. The treatment of TBI with human marrow stromal cells impregnated into collagen scaffold: functional outcome and gene expression profile. Brain Res. 2011 Jan 31;1371:129-39. doi: 10.1016/j.brainres.2010.10.088. Epub 2010 Nov 6. PMID:21062621; PMC3022100
Sullivan PG, Sebastian AH, Hall ED. Therapeutic window analysis of the neuroprotective effects of cyclosporine A after traumatic brain injury. J Neurotrauma. 2011 Feb;28(2):311-8. doi: 10.1089/neu.2010.1646. Epub 2011 Feb 2. PMID:21142667; PMC3037811
Liu MC, Kobeissy F, Zheng W, Zhang Z, Hayes RL, Wang KK. Dual vulnerability of tau to calpains and caspase-3 proteolysis under neurotoxic and neurodegenerative conditions. ASN Neuro. 2011 Feb 16;3(1):e00051. doi: 10.1042/AN20100012. PMID:21359008; PMC3040574

> Fluid Percussion Injury Model (30 references)

Hemlata, Vasudeva N, Sharma S. In-Vivo And In-Vitro Investigations To Assess Traumatic Brain Injury. CNS Neurol Disord Drug Targets. 2023 Feb 21. doi: 10.2174/1871527322666230221115328. Online ahead of print.
Sabetta Z, Krishna G, Curry T, Adelson PD, Thomas TC. Aging with TBI vs. Aging: 6-month temporal profiles for neuropathology and astrocyte activation converge in behaviorally relevant thalamocortical circuitry of male and female rats. bioRxiv. 2023 Feb 7:2023.02.06.527058. doi: 10.1101/2023.02.06.527058. Preprint.
Heiskanen M, Das Gupta S, Mills JD, van Vliet EA, Manninen E, Ciszek R, Andrade P, Puhakka N, Aronica E, Pitkanen A. Discovery and Validation of Circulating microRNAs as Biomarkers for Epileptogenesis after Experimental Traumatic Brain Injury-The EPITARGET Cohort. Int J Mol Sci. 2023 Feb 1;24(3):2823. doi: 10.3390/ijms24032823.
Chary K, Manninen E, Claessens J, Ramirez-Manzanares A, Grohn O, Sierra A. Diffusion MRI approaches for investigating microstructural complexity in a rat model of traumatic brain injury. Sci Rep. 2023 Feb 8;13(1):2219. doi: 10.1038/s41598-023-29010-3.
Rundfeldt C, Klein P, Boison D, Rotenberg A, D'Ambrosio R, Eastman C, Purnell B, Murugan M, Goodkin HP, Loscher W. Preclinical pharmacokinetics and tolerability of a novel meglumine-based parenteral solution of topiramate and topiramate combinations for treatment of status epilepticus. Epilepsia. 2023 Apr;64(4):888-899. doi: 10.1111/epi.17520. Epub 2023 Feb 12.
Huie JR, Nielson JL, Wolfsbane J, Andersen CR, Spratt HM, DeWitt DS, Ferguson AR, Hawkins BE. Data-driven approach to integrating genomic and behavioral preclinical traumatic brain injury research. Front Bioeng Biotechnol. 2023 Jan 10;10:887898. doi: 10.3389/fbioe.2022.887898. eCollection 2022.
Gao Y, Zhang H, Wang J, Li F, Li X, Li T, Wang C, Li L, Peng R, Liu L, Cui W, Zhang S, Zhang J. Annexin A5 ameliorates traumatic brain injury-induced neuroinflammation and neuronal ferroptosis by modulating the NF-kappaB/HMGB1 and Nrf2/HO-1 pathways. Int Immunopharmacol. 2023 Jan;114:109619. doi: 10.1016/j.intimp.2022.109619. Epub 2022 Dec 21.
Fang Y, Qiu W, Li X, Jin Q, Yan H, Yu N, Zhao J, Tan Y, Zhao Z. A combination of umbilical cord mesenchymal stem cells and monosialotetrahexosy 1 ganglioside alleviates neuroinflammation in traumatic brain injury. Exp Brain Res. 2023 Mar;241(3):713-726. doi: 10.1007/s00221-023-06554-4. Epub 2023 Jan 25.
Agas A, Ravula AR, Ma X, Cheng Y, Belfield KD, Haorah J. Hemolytic iron regulation in traumatic brain injury and alcohol use. Alcohol. 2023 Jan 21;109:1-12. doi: 10.1016/j.alcohol.2023.01.001. Online ahead of print.
Rawat V, Eastman CL, Amaradhi R, Banik A, Fender JS, Dingledine RJ, D'Ambrosio R, Ganesh T. Temporal Expression of Neuroinflammatory and Oxidative Stress Markers and Prostaglandin E2 Receptor EP2 Antagonist Effect in a Rat Model of Epileptogenesis. ACS Pharmacol Transl Sci. 2022 Dec 8;6(1):128-138. doi: 10.1021/acsptsci.2c00189. eCollection 2023 Jan 13.
Frank D, Gruenbaum BF, Semyonov M, Binyamin Y, Severynovska O, Gal R, Frenkel A, Knazer B, Boyko M, Zlotnik A. Assessing Dominant-Submissive Behavior in Adult Rats Following Traumatic Brain Injury. J Vis Exp. 2022 Dec 16;(190). doi: 10.3791/64548.
Kundu S, Singh S. Protective Mechanisms of 3-Acetyl-11-keto-beta-Boswellic Acid and Piperine in Fluid Percussion Rat Model of Traumatic Brain Injury Targeting Nrf2 and NFkB Signaling. Neurotox Res. 2023 Feb;41(1):57-84. doi: 10.1007/s12640-022-00628-x. Epub 2022 Dec 28.
Gilfarb R, Tapp Z, Lemanski E, Velasquez J, Cornelius S, Kokiko-Cochran ON, Leuner B. Multiparity Differentially Affects Specific Aspects of the Acute Neuroinflammatory Response to Traumatic Brain Injury in Female Mice. Neuroscience. 2023 Feb 10;511:86-99. doi: 10.1016/j.neuroscience.2022.12.011. Epub 2022 Dec 16.
Heiskanen M, Jaaskelainen O, Manninen E, Das Gupta S, Andrade P, Ciszek R, Grohn O, Herukka SK, Puhakka N, Pitkanen A. Plasma Neurofilament Light Chain (NF-L) Is a Prognostic Biomarker for Cortical Damage Evolution but Not for Cognitive Impairment or Epileptogenesis Following Experimental TBI. Int J Mol Sci. 2022 Dec 2;23(23):15208. doi: 10.3390/ijms232315208.
Li Q, Zhao P, Wen Y, Zou Z, Qin X, Tan H, Gong J, Wu Q, Zheng C, Zhang K, Huang Q, Maegele M, Gu Z, Li L. POLYDATIN AMELIORATES TRAUMATIC BRAIN INJURY-INDUCED SECONDARY BRAIN INJURY BY INHIBITING NLRP3-INDUCED NEUROINFLAMMATION ASSOCIATED WITH SOD2 ACETYLATION. Shock. 2023 Mar 1;59(3):460-468. doi: 10.1097/SHK.0000000000002066. Epub 2022 Dec 8.
Doust YV, Bindoff A, Holloway OG, Wilson R, King AE, Ziebell JM. Temporal changes in the microglial proteome of male and female mice after a diffuse brain injury using label-free quantitative proteomics. Glia. 2023 Apr;71(4):880-903. doi: 10.1002/glia.24313. Epub 2022 Dec 5.
Li T, Li L, Peng R, Hao H, Zhang H, Gao Y, Wang C, Li F, Liu X, Chen F, Zhang S, Zhang J. Abrocitinib Attenuates Microglia-Mediated Neuroinflammation after Traumatic Brain Injury via Inhibiting the JAK1/STAT1/NF-kappaB Pathway. Cells. 2022 Nov 13;11(22):3588. doi: 10.3390/cells11223588.
Lopez-Preza FI, Huerta de la Cruz S, Santiago-Castaneda C, Silva-Velasco DL, Beltran-Ornelas JH, Tapia-Martinez J, Sanchez-Lopez A, Rocha L, Centurion D. Hydrogen sulfide prevents the vascular dysfunction induced by severe traumatic brain injury in rats by reducing reactive oxygen species and modulating eNOS and H(2)S-synthesizing enzyme expression. Life Sci. 2023 Jan 1;312:121218. doi: 10.1016/j.lfs.2022.121218. Epub 2022 Nov 23.
Manninen E, Chary K, De Feo R, Hamalainen E, Andrade P, Paananen T, Sierra A, Tohka J, Grohn O, Pitkanen A. Acute Hippocampal Damage as a Prognostic Biomarker for Cognitive Decline but Not for Epileptogenesis after Experimental Traumatic Brain Injury. Biomedicines. 2022 Oct 27;10(11):2721. doi: 10.3390/biomedicines10112721.
Fronczak KM, Roberts A, Svirsky S, Parry M, Holets E, Henchir J, Dixon CE, Carlson SW. Assessment of behavioral, neuroinflammatory, and histological responses in a model of rat repetitive mild fluid percussion injury at 2 weeks post-injury. Front Neurol. 2022 Oct 20;13:945735. doi: 10.3389/fneur.2022.945735. eCollection 2022.
Wangler LM, Bray CE, Packer JM, Tapp ZM, Davis AC, O'Neil SM, Baetz K, Ouvina M, Witzel M, Godbout JP. Amplified Gliosis and Interferon-Associated Inflammation in the Aging Brain following Diffuse Traumatic Brain Injury. J Neurosci. 2022 Nov 30;42(48):9082-9096. doi: 10.1523/JNEUROSCI.1377-22.2022. Epub 2022 Oct 18.
Zou S, Chen W, Ding H, Qi Y, Wang Z, Fu J, Ren D, Duan J, Jiang B, Feng J. Involvement of Autophagy in the Protective Effects of Ginsenoside Rb1 in a Rat Model of Traumatic Brain Injury. Eur J Drug Metab Pharmacokinet. 2022 Nov;47(6):869-877. doi: 10.1007/s13318-022-00799-0. Epub 2022 Oct 5.
Michinaga S, Sonoda K, Inazuki N, Ezaki M, Awane H, Shimizu K, Hishinuma S, Mizuguchi H. Selective histamine H(2) receptor agonists alleviate blood-brain barrier disruption by promoting the expression of vascular protective factors following traumatic brain injury in mice. J Pharmacol Sci. 2022 Nov;150(3):135-145. doi: 10.1016/j.jphs.2022.08.003. Epub 2022 Aug 19.
Arnaud FG, Haque LA, Barkei ME, Morris ME, Hubbell JN, Coschigano N, Gosztyla LC, Malone CDL, Scultetus AH. Effects of sequential aeromedical evacuations following traumatic brain injury in swine. Injury. 2022 Nov;53(11):3596-3604. doi: 10.1016/j.injury.2022.09.004. Epub 2022 Sep 15.
Abdul-Muneer PM, Saikia BB, Bhowmick S. Synergistic effect of mild traumatic brain injury and alcohol aggravates neuroinflammation, amyloidogenesis, tau pathology, neurodegeneration, and blood-brain barrier alterations: Impact on psychological stress. Exp Neurol. 2022 Dec;358:114222. doi: 10.1016/j.expneurol.2022.114222. Epub 2022 Sep 9.
Allioux C, Achaintre L, Cheataini F, Balanca B, Marinesco S. Animal welfare assessment after severe traumatic brain injury in rats. Lab Anim. 2022 Dec;56(6):528-539. doi: 10.1177/00236772221107269. Epub 2022 Aug 8.
Mercado NM, Zhang G, Ying Z, Gomez-Pinilla F. Traumatic brain injury alters the gut-derived serotonergic system and associated peripheral organs. Biochim Biophys Acta Mol Basis Dis. 2022 Nov 1;1868(11):166491. doi: 10.1016/j.bbadis.2022.166491. Epub 2022 Jul 25.
Hoffman AN, Watson S, Chavda N, Lam J, Hovda DA, Giza CC, Fanselow MS. Increased Fear Generalization and Amygdala AMPA Receptor Proteins in Chronic Traumatic Brain Injury. J Neurotrauma. 2022 Nov;39(21-22):1561-1574. doi: 10.1089/neu.2022.0119. Epub 2022 Sep 9.
Griffiths DR, Law LM, Young C, Fuentes A, Truran S, Karamanova N, Bell LC, Turner G, Emerson H, Mastroeni D, Gonzales RJ, Reaven PD, Quarles CC, Migrino RQ, Lifshitz J. Chronic Cognitive and Cerebrovascular Function after Mild Traumatic Brain Injury in Rats. J Neurotrauma. 2022 Oct;39(19-20):1429-1441. doi: 10.1089/neu.2022.0015.
Nakuci J, McGuire M, Schweser F, Poulsen D, Muldoon SF. Differential Patterns of Change in Brain Connectivity Resulting from Severe Traumatic Brain Injury. Brain Connect. 2022 Nov;12(9):799-811. doi: 10.1089/brain.2021.0168. Epub 2022 May 5.

> Weight-Drop Injury Model (432 references)

Showing the first 95 of 432 references. Additional references will be added in future batches.

Tang YP, Noda Y, Hasegawa T, Nabeshima T. Effects of VA-045 on learning and memory deficits in traumatic brain injury (TBI)-induced retrograde and anterograde amnesic mice Br J Pharmacol. 1997 Sep;122(2):257-64. doi: 10.1038/sj.bjp.0701385. PMID:9313933 **In Model Catalog**
Leinhase I, Rozanski M, Harhausen D, Thurman JM, Schmidt OI, Hossini AM, Taha ME, Rittirsch D, Ward PA, Holers VM, Ertel W, Stahel PF. Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice J Neuroinflammation. 2007 May 2;4:13. doi: 10.1186/1742-2094-4-13. PMID:17474994 **In Model Catalog**
Payette DJ, Xie J, Shirwany N, Guo Q. Exacerbation of apoptosis of cortical neurons following traumatic brain injury in par-4 transgenic mice Int J Clin Exp Pathol. 2008 Jan 1;1(1):44-56. PMID:18784822 **In Model Catalog**
Jin W, Wang H, Yan W, Xu L, Wang X, Zhao X, Yang X, Chen G, Ji Y. Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injury Mediators Inflamm. 2008;2008:725174. doi: 10.1155/2008/725174. Epub 2009 Jan 25. PMID:19190763
Ding JY, Kreipke CW, Speirs SL, Schafer P, Schafer S, Rafols JA. Hypoxia-inducible factor-1alpha signaling in aquaporin upregulation after traumatic brain injury Neurosci Lett. 2009 Mar 27;453(1):68-72. doi: 10.1016/j.neulet.2009.01.077. Epub 2009 Feb 4. PMID:19429018 **In Model Catalog**
Potts MB, Adwanikar H, Noble-Haeusslein LJ. Models of traumatic cerebellar injury Cerebellum. 2009 Sep;8(3):211-21. doi: 10.1007/s12311-009-0114-8. Epub 2009 Jun 5. PMID:19495901
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Israelsson C, Wang Y, Kylberg A, Pick CG, Hoffer BJ, Ebendal T. Closed head injury in a mouse model results in molecular changes indicating inflammatory responses J Neurotrauma. 2009 Aug;26(8):1307-14. doi: 10.1089/neu.2008.0676. PMID:19317611 **In Model Catalog**
Khuman J, Meehan WP 3rd, Zhu X, Qiu J, Hoffmann U, Zhang J, Giovannone E, Lo EH, Whalen MJ. Tumor necrosis factor alpha and Fas receptor contribute to cognitive deficits independent of cell death after concussive traumatic brain injury in mice J Cereb Blood Flow Metab. 2011 Feb;31(2):778-89. doi: 10.1038/jcbfm.2010.172. Epub 2010 Oct 13. PMID:20940727 **In Model Catalog**
Wang GH, Jiang ZL, Li YC, Li X, Shi H, Gao YQ, Vosler PS, Chen J. Free-radical scavenger edaravone treatment confers neuroprotection against traumatic brain injury in rats J Neurotrauma. 2011 Oct;28(10):2123-34. doi: 10.1089/neu.2011.1939. Epub 2011 Sep 27. PMID:21732763 **In Model Catalog**
Alder J, Fujioka W, Lifshitz J, Crockett DP, Thakker-Varia S. Lateral fluid percussion: model of traumatic brain injury in mice J Vis Exp. 2011 Aug 22;(54):3063. doi: 10.3791/3063. PMID:21876530
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Lopez NE, Krzyzaniak MJ, Blow C, Putnam J, Ortiz-Pomales Y, Hageny AM, Eliceiri B, Coimbra R, Bansal V. Ghrelin prevents disruption of the blood-brain barrier after traumatic brain injury J Neurotrauma. 2012 Jan 20;29(2):385-93. doi: 10.1089/neu.2011.2053. Epub 2011 Oct 26. PMID:21939391 **In Model Catalog**
Bansal V, Ryu SY, Blow C, Costantini T, Loomis W, Eliceiri B, Baird A, Wolf P, Coimbra R. The hormone ghrelin prevents traumatic brain injury induced intestinal dysfunction J Neurotrauma. 2010 Dec;27(12):2255-60. doi: 10.1089/neu.2010.1372. Epub 2010 Nov 2. PMID:20858122 **In Model Catalog**
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Probst C, Mirzayan MJ, Mommsen P, Zeckey C, Tegeder T, Geerken L, Maegele M, Samii A, van Griensven M. Systemic inflammatory effects of traumatic brain injury, femur fracture, and shock: an experimental murine polytrauma model Mediators Inflamm. 2012;2012:136020. doi: 10.1155/2012/136020. Epub 2012 Mar 4. PMID:22529516 **In Model Catalog**
Wu Q, Xuan W, Ando T, Xu T, Huang L, Huang YY, Dai T, Dhital S, Sharma SK, Whalen MJ, Hamblin MR. Low-level laser therapy for closed-head traumatic brain injury in mice: effect of different wavelengths Lasers Surg Med. 2012 Mar;44(3):218-26. doi: 10.1002/lsm.22003. Epub 2012 Jan 24. PMID:22275301 **In Model Catalog**
Chao PK, Lu KT, Jhu JY, Wo YY, Huang TC, Ro LS, Yang YL. Indomethacin protects rats from neuronal damage induced by traumatic brain injury and suppresses hippocampal IL-1beta release through the inhibition of Nogo-A expression J Neuroinflammation. 2012 Jun 7;9:121. doi: 10.1186/1742-2094-9-121. PMID:22676811 **In Model Catalog**
Wei XE, Zhang YZ, Li YH, Li MH, Li WB. Dynamics of rabbit brain edema in focal lesion and perilesion area after traumatic brain injury: a MRI study J Neurotrauma. 2012 Sep 20;29(14):2413-20. doi: 10.1089/neu.2010.1510. Epub 2011 Oct 4. PMID:21675826 **In Model Catalog**
Albert-Weissenberger C, Stetter C, Meuth SG, Gobel K, Bader M, Siren AL, Kleinschnitz C. Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activation J Cereb Blood Flow Metab. 2012 Sep;32(9):1747-56. doi: 10.1038/jcbfm.2012.62. Epub 2012 May 9. PMID:22569191 **In Model Catalog**
Yoon YS, Yu KP, Kim H, Kim HI, Kwak SH, Kim BO. The effect of electric cortical stimulation after focal traumatic brain injury in rats Ann Rehabil Med. 2012 Oct;36(5):596-608. doi: 10.5535/arm.2012.36.5.596. Epub 2012 Oct 31. PMID:23185723 **In Model Catalog**
Khaksari M, Mahmmodi R, Shahrokhi N, Shabani M, Joukar S, Aqapour M. The Effects of Shilajit on Brain Edema, Intracranial Pressure and Neurologic Outcomes following the Traumatic Brain Injury in Rat Iran J Basic Med Sci. 2013 Jul;16(7):858-64. PMID:23997917 **In Model Catalog**
Schwulst SJ, Trahanas DM, Saber R, Perlman H. Traumatic brain injury-induced alterations in peripheral immunity J Trauma Acute Care Surg. 2013 Nov;75(5):780-8. doi: 10.1097/TA.0b013e318299616a. PMID:24158195 **In Model Catalog**
Rachmany L, Tweedie D, Rubovitch V, Yu QS, Li Y, Wang JY, Pick CG, Greig NH. Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-alpha PLoS One. 2013 Nov 28;8(11):e79837. doi: 10.1371/journal.pone.0079837. eCollection 2013. PMID:24312187 **In Model Catalog**
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Zhou Y, Wang HD, Zhou XM, Fang J, Zhu L, Ding K. N-acetylcysteine amide provides neuroprotection via Nrf2-ARE pathway in a mouse model of traumatic brain injury Drug Des Devel Ther. 2018 Dec 4;12:4117-4127. doi: 10.2147/DDDT.S179227. eCollection 2018. PMID:30584276 **In Model Catalog**
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> Blast Injury Model (53 references)

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Harper MM, Boehme N, Dutca LM, Anderson MG. The Retinal Ganglion Cell Response to Blast-Mediated Traumatic Brain Injury Is Genetic Background Dependent Invest Ophthalmol Vis Sci. 2021 Jun 1;62(7):13. doi: 10.1167/iovs.62.7.13. PMID:34106210; PMC8196410 **In Model Catalog**
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Wang C, Shao C, Zhang L, Siedlak SL, Meabon JS, Peskind ER, Lu Y, Wang W, Perry G, Cook DG, Zhu X. Oxidative Stress Signaling in Blast TBI-Induced Tau Phosphorylation Antioxidants (Basel). 2021 Jun 15;10(6):955. doi: 10.3390/antiox10060955. PMID:34203583; PMC8232162 **In Model Catalog**
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> Closed-Head Impact Model of Engineered Rotational Acceleration (CHIMERA) Model (48 references)

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